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Sunday, March 16, 2008

Abercrombie allegra

allegra


The report of the surplus of fexofenadine be set to be, it is not something that, as a result, has created the effect and East become so. Death to 5000 mg / kg, has not been the case to the test of Souris, which is 110 times for the man of the highest dose adult who is appointed. As above for research on the dose where the man in the adult is designated with the same centralization 400 times at which Death does not agree with demonstrated rut / rat. The search for the man when reached at a dose of 1 month twice daily 690 magnesium false Medicine compared to the single dose of 800 magnesium Adverse clinically important. To create from Piperidine, two phenyl groups are translated using the Grignard reaction of the ester of higher education which gives alcohol first. As with the amine group of aldehyde, which is protected, and then the alkyl group is introduced, and is recovered by the aldehyde and acid Deprotection. As for the rest of the molecule, it is created by the double alkylation of iodomethane with carbanion is Obtained from nitrile. As for the group of nitrile in the carboxyl group acid then add water, it is disassembled. (After workup) in order to create a mixture of organolithium who can connect with the aldehyde Part, in order to give that to fexofenadine bromide then it is aryl lithiated.

 
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